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Biolog
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56 Lediga jobb

Laboratorieingenjör till QC mikrobiologi, Uppsala

Arbetsgivare / Ort: Randstad AB
Omfattning / Varaktighet: Heltid / 6 månader eller längre
Lönetyp: Fast månads- vecko- eller timlön
Ansök senast idag
Publicerad: 2021-10-06
Källa: Arbetsförmedlingen
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Om jobbet

Arbetsbeskrivning

Är du intresserad av QC-verksamhet och mikrobiologi och där du genom din expertis får lösa problem och aktivt delta i arbetet med att förbättra och utveckla verksamheten? Är du nyfiken, målmedveten och strukturerad? Då är denna spännande och varierande tjänst något för dig. Vi på Ranstad Life Sciences söker nu laboratorieingenjörer för konsultuppdrag hos ett större internationellt bolag som är stolta över sina produkter och där kollegor, utvecklingsmöjligheterna och den familjära stämningen är några starka sidor. 

Randstad Life Sciences är specialister inom naturvetenskap. Som konsult hos oss får du konkurrenskraftig lön, förmåner och kollektivavtalade villkor. Din konsultchef, som alltid finns nära till hands, ser till att du får varierande och utvecklande uppdrag på olika företag, inom olika branscher. Hos Randstad Life Sciences står din personliga utveckling i fokus, och du erbjuds ett stort nätverk och många sociala aktiviteter.

Ansvarsområden

Tjänsten som laboratorieingenjör är i den operativa sektionen på QC mikrobiologi och innebär att utföra mikrobiologiska analyser på inkommande råvaror, APIer, processprover och färdig produkt samt identifiering av mikroorganismer. I tjänsten ingår också att driva utredningar och förbättringsarbete samt delta i valideringsarbete.

Som laboratorieingenjör är dina huvudsakliga arbetsuppgifter och ansvarsområden:
• Analys av steriltest i renrum (B-klass).
• Inslussning av produkter och material till renrum (från O-klassat till B-klass).
• Analys av koktest, endotoxintest och totalantal mikroorganismer (bioburden).
• Att självständigt utföra det dagliga arbetet som avläsningar av prover, rapportering av resultat, granskning, trendning och beställning av förbrukningsmaterial etc.
• Att självständigt driva avvikelseutredningar inom arbetsområdet (initiera, utreda, dokumentera).
• Att självständigt uppdatera instruktioner och driva förbättringsarbete.
• Utföra identifiering av mikroorganismer samt utföra ankomstkontroller av stammar och substrat.
• Delta i avdelningens valideringsarbete.

Som person bör du vara flexibel, noggrann, ha god kommunikationsförmåga, är nyfiken, målmedveten och strukturerad. Det är viktigt att du har mycket god samarbetsförmåga och tar ansvar så att gruppen levererar enligt satta tidslinjer och kvalitetskrav. Du behöver ha förmåga att kunna driva administrativa uppgifter parallellt med analysarbete och anpassa ditt arbete efter de prioriteringar som gäller. Du är också självgående i ditt arbete, tar egna initiativ och påvisar gott omdöme. I rollen agerar du utifrån de riktlinjer och krav som styr arbetet inom läkemedelsindustrin, det krävs att du strukturerat och noggrant utför och dokumenterar dina arbetsuppgifter.

Arbetstider

Konsultuppdrag 6 månader med möjlighet till förlängning. Arbetstiden är förlagd till dagtid, heltid.

Kvalifikationer

• Akademisk utbildning inom bioteknik, biologi, mikrobiologi eller annan motsvarande utbildning.
• Erfarenhet av mikrobiologisk kvalitetskontroll och analysarbete.
• God förmåga att utrycka dig på engelska och svenska i tal och skrift.

• Erfarenhet av sådant arbete inom läkemedelsindustrin är meriterande.
• Erfarenhet att ha arbetat med renrumsarbete i B-klass, analyserfarenhet av steriltest, endotoxintest, bioburdentest, identifiering och/eller mikrobiologiska utredningar är meriterande.

Ansökan

Vi som arbetar på Randstad Life Sciences har alla en bakgrund inom naturvetenskap. Det betyder att vi förstår vad du har för erfarenhet och vad ett lämpligt nästa steg i din karriär kan vara. Vi strävar efter att bli din karriärpartner inom life science för en lång tid framöver. Hos Randstad Life Sciences står din personliga utveckling i fokus, och det är en självklarhet för oss att du får en närvarande konsultchef som med stort engagemang finns tillgänglig här i Uppsala. Hos oss får du fast månadslön, förmåner och kollektivavtalade villkor. Din anställning omfattas givetvis även av försäkringar, tjänstepension, friskvårdsbidrag och företagshälsovård.

Som information, så görs  alltid en bakgrundskontroll i slutet av intervju och anställningsprocessen, vilket är en del av våra normala processer.

Arbetsgivare: Randstad Life Sciences

Plats: Uppsala

Sista ansökningsdag: 2021-08-08, urval och intervjuer kommer att ske löpande. Tjänsten kan komma att bli tillsatt innan sista ansökningsdag, ansök därför så snart som möjligt.
Vi tar inte emot ansökningar via post eller e-mail.

Kontaktperson: Emil Hamnevik, konsultchef, [email protected]

Om företaget

Med över 600 000 anställda i omkring 40 länder är Randstad världsledande inom HR-tjänster och erbjuder bemannings-, konsult- och rekryteringslösningar inom alla kompetensområden. Vi erbjuder även interim management, executive search och omställningstjänster. Vi har ett stort nätverk av bolag och kandidater vilket innebär att vi förmedlar hundratals jobb inom olika branscher, från Kiruna i norr till Malmö i söder. Vår ambition är att vara den bästa arbetsgivaren på marknaden.

Genom att kombinera vår passion för människor med kraften i dagens teknologi hjälper vi människor och organisationer att nå deras sanna potential. Vi kallar det Human Forward.
Arbetsgivare
Randstad AB
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Thesis work: ER stress responses in primary lung cells

Arbetsgivare / Ort: Randstad AB
Omfattning / Varaktighet: Heltid / 6 månader eller längre
Lönetyp: Fast månads- vecko- eller timlön
Ansök senast idag
Publicerad: 2021-10-11
Källa: Arbetsförmedlingen
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Kvalifikationer
Arbetslivserfarenhet
Krav
  • Biolog

Om jobbet

Job description

Modulation of ER stress responses in primary lung cells

Thesis project:
30 credits
Student location:
AstraZeneca, Gothenburg, Sweden
Start:
January 2022

Endoplasmic reticulum (ER) stress, arising from perturbed protein homeostasis, activates the unfolded protein response (UPR) that leads to a myriad of downstream cellular events. We believe that dysregulation or defective UPR responses plays an important role in chronic respiratory diseases such as COPD or IPF. This project aims to investigate and modulate the UPR pathway activation in primary lung cells of different origin to identify the major cell types targeted by ER stress and its specific downstream UPR responses.

Responsibilities

In this placement, the student will be part of a cross-functional team within Research and Early Development, Respiratory and Immunology (R&I), building scientific knowledge around disease-causing molecular mechanisms and identification of novel targets for treatment. Specifically, the student will be working closely with a team investigating the role of ER stress in COPD and IPF.
 
Objectives and goals:
  1. Establish protocols to induce ER stress and monitor the UPR and associated respiratory disease-relevant biological pathways in primary lung cells.
  2.  Acquire extensive training in fundamental molecular and cell biology techniques, including qPCR, cell imaging, Western blot and other cellular/protein assays. 
  3. Contribute scientifically to the cross-functional ER stress team.
  4. Get insight in project work and drug discovery. 

Qualifications

Essential Requirements
  • Good networking skills and interpersonal skills.
  • Interest and curiosity in molecular biology and the experimental work behind drug discovery.
  • Ability to work independently.
  • Understanding of cell and molecular biology.
  • Written and oral communication skills in English.

Desirable Requirements 
  • Experience in cell culture.
  • Experience in molecular cell biology techniques eg. qPCR and Western blot.
  • Skilled in problem solving.

Application

Randstad Life Sciences is cooperating with AstraZeneca in this recruitment process. We only handle applications sent through Randstad’s website.

All chosen candidates need to pass a background check and an alcohol and drug test before starting the project.

Deadline for application: 2021-10-20

For more information: Veronika Knudsen [email protected] or Kerstin Karlsson [email protected]

About the company

At AstraZeneca, we turn ideas into life changing medicines and strive to continuously meet the unmet needs of patients worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.

Our Gothenburg site is one of AstraZeneca's three strategic science centers. We thrive in a multinational environment working cross-functionally across the globe with AstraZeneca colleagues as well as academic and industry partners. Our way of life is to foster a working environment that nurtures collaboration, openness and innovation. Therefore, we have created space for meetings, socializing and relaxation, where spontaneous meetings can give birth to new innovations. The unexpected ideas or thoughts that can come from a chat over something as simple as a cup of  coffee or a stroll on our “walk and talk” meeting trail. AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.

Arbetsgivare
Randstad AB
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CVRM research - metabolism in vitro team

Arbetsgivare / Ort: Randstad AB
Omfattning / Varaktighet: Heltid / 6 månader eller längre
Lönetyp: Fast månads- vecko- eller timlön
Ansök senast idag
Publicerad: 2021-10-11
Källa: Arbetsförmedlingen
VISA MER
Kvalifikationer
Arbetslivserfarenhet
Krav
  • Biolog

Om jobbet

Job description

Cardiovascular Renal and Metabolism (CVRM) Research – Metabolism In Vitro Team - Gothenburg

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because an opportunity no matter how small can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognising their potential.

The AstraZeneca CVRM Research group in Gothenburg is seeking to recruit a high calibre scientist to enable progression of a growing drug project portfolio. Highly motivated scientists are encouraged to apply for the opportunity to join our team of professionals who are passionate about advancing science, to discover and develop novel therapeutics that will benefit patients.
Role Overview

You will play an active role in implementing and executing scientific research and development within the CVRM Metabolism in vitro team, enabling the prosecution of a rapidly growing portfolio of small molecule and biologics drug projects. This is a "hands-on," laboratory based scientific and technical role in our in vitro metabolism team supporting projects from target validation to lead optimisation phases.
Role specifics

This position will be laboratory based and you will be responsible for several technical and experimental processes to support the CVRM Research group.

Responsibilities

  • Responsibility for design, execution and analysis of in vitro and ex vivo assays.
  • Predominantly functional and cellular screens supporting Target Validation, Lead Isolation and Lead Optimisation for the CVRM Research Area.
  • Communicate results, conclusions and recommendations to colleagues, line manager and multi-disciplinary teams.
  • Perform extended and specialized characterization when required for projects.
  • Record experiments in lab books and databases.
  • Play a leading role in assay development and optimization of disease relevant primary and transfected cell assays.
  • You would report to an expert member of staff and would be encouraged to be able to plan your daily work within direction set by your supervisor.
You will:
  • Be asked to provide interpretation of assay results
  • Work within a line and/or matrix/project team.
  • Demonstrates scientific rigor in assessing own data and that of others.

Qualifications

Essential
  • Be a "hands-on" expert with in vitro models and methodologies.
  • Enthusiasm for laboratory work, scientific curiosity
  • Experience in running in vitro biochemical and cellular assays to provide potency and activity readouts, including use of primary and recombinant cell lines.
  • Significant cell culture experience.
  • Experience of working with medium to high density microtitre plate technologies
  • Experience in data analysis and interpretation
  • Experience of working in accordance with established SOPs and codes of conduct.
  • Capability to work seamlessly with cross-functional project teams to provide high quality data in a timely manner.
  • Demonstrable ability to work within a line and/or matrix/ cross-functional project team.
  • Strong interest in providing materials and data for scientifically challenging work
  • Strong organizational, time management and communication skills
  • Strong, demonstrable analytical ability
  • Good oral and written communications skills
Desirable
  • Background in metabolic disease research areas.
  • Experience of working with disease relevant primary cell assays associated with one or more of the following disease areas: diabetes, obesity, NASH or dyslipidaemia.
  • Experience of use of robotics for assays and /or sample handling.
  • Experience working in pharmaceutical or biotech environment
Behavioral competencies
  • Hard working, organized, balanced and meticulous with an ability to work well under pressure.
  • Adaptable and a team player with a conscientious attitude and enthusiasm.
  •  Desire to learn and build on the role

Education
Degree in one of the Life Sciences disciplines and equivalent post-graduate or industry experience.

Application

Deadline 2021-10-17, selection and interviews will be ongoing. The position may be filled before the last day of application, therefore, apply as soon as possible.

For more information: Kerstin Karlsson [email protected] or Veronika Knudsen [email protected]

About the company

Randstad Life Sciences specializes in the field of science and is part of Randstad, the world leader in recruitment and consulting with operations in 38 countries. With this global network, in combination with our strong local foundation, we can offer a wide range of varied and developing assignments and jobs for you who are a specialist in life science. Our mission is to help you reach your true potential with your career in focus!

Arbetsgivare
Randstad AB
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Tissue Imaging Scientist - Imaging & AI at AstraZeneca

Arbetsgivare / Ort: Astrazeneca AB
Omfattning / Varaktighet: Heltid / Tills vidare
Lönetyp: Fast månads- vecko- eller timlön
Ansök senast idag
Publicerad: 2021-09-22
Källa: Arbetsförmedlingen
VISA MER
Om jobbet
Do you have expertise in tissue imaging, and would like to be a part of an Imaging & AI team who has direct impact on drug development, playing a key role in bringing medicines to patients? Then come join us at AstraZeneca in Gothenburg Sweden, as our new Tissue Imaging Scientist. As a Tissue Imaging Scientist you will play a pivotal role in delivering high quality imaging data, employing core histology and advanced molecular techniques, involving (multiplex) immunohistochemistry, immunofluorescence and in situ hybridisation method development as well as antibody characterisation to support projects. In this role you will be a part of our Imaging & AI team working within the Clinical Pharmacology and Safety Sciences (CPSS) organisation. Clinical Pharmacology and Safety Sciences (CPSS) is changing the way imaging technologies are combined to offer unprecedented insight and impact. Our imaging hubs combine data from histology, digital pathology, multiplex assays, advanced molecular imaging techniques (including mass spectrometry imaging) and a full suite of in vivo imaging technologies. Thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment. What you'll do: As a Tissue Imaging Scientist you will be involved in the delivery of the histology component of early investigative in vivo safety studies, working with the local imaging hub lead, pathologists and study directors to deliver data to required quality standards and timelines. In addition, you will provide expert application of imaging technologies to advise on efficacy of new therapies. You will also lead the design of tissue imaging endpoints, primarily with histological and molecular pathology-based techniques, and provide general and hypothesis-driven scientific advice on specific topics to the team. To do this, you need to have a strong understanding of the practices, principles and concepts associated with a variety of study types using both histological/molecular pathology techniques and other tissue imaging technologies within the group. Additional responsibilities: * Help develop and apply advanced molecular techniques including multiplex immunohistochemistry/immunofluorescence and in situ hybridisation. * Dynamically deliver standard safety histology endpoints, directly or through CRO outsourcing. * Maintain knowledge internally and externally of new trends in tissue imaging technology, experimental techniques/equipment and introduce new methods and instrumentation as required and agreed with the Imaging & AI Leadership Team. * Learn to perform basic image analysis using commercial software solutions. Essential in the role: * PhD or Graduate (mouse biology, molecular biology, biotechnology etc.) with strong experience in a relevant field. * Expert knowledge in at least one of the following: immunohistochemistry, immunofluorescence, in situ hybridisation. * Knowledge of histomorphology of mammalian tissue/s. * Independent experimental design, critical data analysis (including statistics) and reporting. * Comprehensive core knowledge of histology techniques. * Problem-solving skills related to molecular pathology data analysis. We also believe that the successful candidate enjoys collaborating, communicating and being a supportive colleague in our great team. This goes hand in hand with your problem-solving skills and strong delivery and goal focus. If you possesses leadership skills within small teams and on individual projects that's a plus to take on this role. Desirable in the role: * Experience in the pharmaceutical industry or hospital molecular pathology laboratory. * Practical knowledge of multiplex immunohistochemistry/immunofluorescence methodology. * Experience in image analysis using commercial software solutions. * Understanding of other disciplines within pharmaceutical R&D. Why AstraZeneca? Be encouraged and supported to think creatively in our dynamic environment. Here we are free from fear of failure, free to ask the right questions and make bold decisions. Embrace an environment built on lifelong learning. Never complacent, we seek opportunities to expand our knowledge. The place to build a long-term meaningful career. So, what's next? If this sounds like your next challenge - welcome to apply today! We look forward to get to know you better, please submit your application no later than October 19th, 2021. For more information about the position please contact Hiring Manager, Bjarki Johannesson at [email protected] Where can I find out more? Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html Life in Gothenburg: https://www.movetogothenburg.com/ About BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html
Arbetsgivare
Astrazeneca AB
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Thesis work: 30 credits, AstraZeneca Gothenburg

Arbetsgivare / Ort: Randstad AB
Omfattning / Varaktighet: Heltid / 6 månader eller längre
Lönetyp: Fast månads- vecko- eller timlön
Ansök senast idag
Publicerad: 2021-10-01
Källa: Arbetsförmedlingen
VISA MER
Kvalifikationer
Arbetslivserfarenhet
Krav
  • Biolog

Om jobbet

Job description

Developing a method for characterizing and improving  stem cell differentiation

Are you a master student with a hunger for science and eager to learn more about stem cell differentiation and the next generation therapeutics? Do you like molecular and cellular biology techniques and are looking for an inspiring master thesis project starting in the spring 2022? Then this project at the new Cell Therapy Department at AstraZeneca could be interesting to You!

Thesis project: 30 credits
Student location: AstraZeneca, Gothenburg, Sweden
Start: January 2022

Introduction
Biopharmaceuticals R&D is now building a new cell therapy department with the goal to establish AstraZeneca as a world-leader in the stem cell field and to build a competitive pipeline within cell therapy across disease areas within Cardiovascular, Renal and Metabolism (CVRM) and Respiratory and Inflammation (R&I). By directing differentiation of pluripotent stem cells into precursor cells or to mature cell types, novel therapies can be developed targeting a wide range of diseases such as heart failure, kidney and liver diseases.

The project aims to develop a novel analytical method that will be used for optimizing differentiation protocols.

Responsibilities

The primary focus of the project will be to culture pluripotent stem cells and differentiate them towards cardiac cells. Samples from the differentiation process will be collected and analyzed, e.g. using ELISA and flow cytometry. 

Qualifications

  • A strong interest in stem cell science.
  • Highly motivated, having a scientific mindset and can easily comprehend and apply ideas from the literature. 
  • Ability to watch & learn, and then perform experiments on your own, with some guidance.
  • Good organizational skills.
  • Written and oral communication skills in English.
  • Cell culture experience. 

Application

Randstad Life Sciences is cooperating with AstraZeneca in this recruitment process. We only handle applications sent through Randstad’s website.

All chosen candidates need to pass a background check and an alcohol and drug test before starting the project.

Deadline for application: 2021-10-20

For more information: Veronika Knudsen [email protected] or Kerstin Karlsson [email protected]

About the company

At AstraZeneca, we turn ideas into life changing medicines and strive to continuously meet the unmet needs of patients worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.

Our Gothenburg site is one of AstraZeneca's three strategic science centers. We thrive in a multinational environment working cross-functionally across the globe with AstraZeneca colleagues as well as academic and industry partners. Our way of life is to foster a working environment that nurtures collaboration, openness and innovation. Therefore, we have created space for meetings, socializing and relaxation, where spontaneous meetings can give birth to new innovations. The unexpected ideas or thoughts that can come from a chat over something as simple as a cup of  coffee or a stroll on our “walk and talk” meeting trail. AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.

Arbetsgivare
Randstad AB
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