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Evolutionsbiolog

Evolutionsbiolog

19 Lediga jobb

Senior / Principal Medical Writer

Arbetsgivare / Ort: LARIX A/S
Omfattning / Varaktighet: Heltid / Tills vidare
Lönetyp: Fast månads- vecko- eller timlön
Ansök senast 30 september (19 dagar kvar)
Publicerad: 2021-08-20
Källa: Arbetsförmedlingen
Kvalifikationer
Färdigheter
Meriterande
  • Klinisk prövning

Språk
Meriterande
  • Engelska

Om jobbet
Jobbeskrivelse: Are you an experienced medical writer looking for a new challenge in a dynamic and responsible position? Would you enjoy working with different customers and projects either in-house or based at the client's office? If so, Larix offers you the opportunity to work in a stimulating environment, with the possibility to influence your work and responsibilities. We are now seeking a Senior or Principal Medical Writer to join our team in Herlev, Denmark and Lund, Sweden. What you will do: Medical writing at Larix involves working on a range of different projects, some only concerning the Medical Writing department, others including full-service projects within the clinical and medical device areas and close collaboration with other departments. Some tasks are carried out in-house at the Larix office, while others are completed as an in-house consultant at the client's location. The tasks are therefore diverse, and we expect that you will see this as an advantage. We have a number of upcoming projects and need a medical writer to join our Medical Writing team. You should also be prepared to work at a client's office in the Copenhagen/Lund area from time to time. The Medical Writing team comprises experienced and enthusiastic employees responsible for a wide variety of documents, including regulatory documents, publications, and applications to the Danish Medicines Council. You will join an experienced and growing team of medical writers and, as we are a relatively small group (currently seven), you will be expected to be actively involved in producing and updating processes and tools to support further development of the Medical Writing function. Who you are The preferred candidate will be proactive, flexible, service-minded, focused on high quality and timely delivery and will have: - At least 5 years of experience as a medical writer of clinical regulatory documents (clinical trial reports, protocols, investigator's brochures) - A university degree in health or life sciences or equivalent, preferably a PhD - Experience in the following, considered an advantage: * Performing literature searches and reviews * Preparing medical device documents according to MEDDEV 2.7.1 rev 4 * Preparing abstracts, posters and manuscripts in a pharmaceutical industry setting - Exceptional ability to plan, drive and coordinate complex medical writing projects in collaboration with many stakeholders - Broad knowledge of several therapeutic areas as well as a general understanding of regulatory requirements, drug development processes, statistical methods and clinical research concepts - Ability to work independently in a structured, proactive way with a quality mindset - Strong communication skills and excellent spoken and written English and Danish (preference) Are you interested? We would love to hear from you. To apply for this position, please forward your application and CV to [email protected] or by applying on LinkedIn using EasyApply. Applications will be handled by our Business Manager in the order they arrive. Please note that vacancies will be filled on a rolling basis after opening and this job posting is also for our candidate pool for future job openings. Therefore, we highly recommend you submit your application as early as possible to be considered for the opportunity of your choice. For more information about the job, please contact Angela Stocks, Director, Medical Writing, at [email protected], +45 8177 8150. Who is Larix? Larix A/S is a Nordic Contract Research Organization (CRO) - we offer full-service solutions within the pharmaceutical, biotech and medical device areas. Our headquarters are located near Copenhagen in the middle of the Medicon Valley region, and we have strong ties to the thriving pharmaceutical and biotech activities in this region. We also have a smaller office at Medicon Village in Lund and a local presence in Oslo and Helsinki. Larix is a part of Alten Group and we work closely with our sister company (Aixial), which gives us all the advantages of being a small, agile and flexible company combined with support from a larger company when it comes to e.g. systems and resources. At Larix, we maintain a friendly atmosphere - we think having fun while working is important, and we prioritize creating a work environment with a healthy work-life balance. We are a relatively small company with approximately 70 employees, and we have all the benefits of being able to collaborate across functions, learn from each other and follow clinical study processes from start to finish.
Arbetsgivare
LARIX A/S
Ansökan
Ansök senast 30 september (19 dagar kvar)

Ansök via mejl
[email protected]
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Thesis work: ER stress responses in primary lung cells

Arbetsgivare / Ort: Randstad AB
Omfattning / Varaktighet: Heltid / 6 månader eller längre
Lönetyp: Fast månads- vecko- eller timlön
Ansök senast idag
Publicerad: 2021-10-11
Källa: Arbetsförmedlingen
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Kvalifikationer
Arbetslivserfarenhet
Krav
  • Biolog

Om jobbet

Job description

Modulation of ER stress responses in primary lung cells

Thesis project:
30 credits
Student location:
AstraZeneca, Gothenburg, Sweden
Start:
January 2022

Endoplasmic reticulum (ER) stress, arising from perturbed protein homeostasis, activates the unfolded protein response (UPR) that leads to a myriad of downstream cellular events. We believe that dysregulation or defective UPR responses plays an important role in chronic respiratory diseases such as COPD or IPF. This project aims to investigate and modulate the UPR pathway activation in primary lung cells of different origin to identify the major cell types targeted by ER stress and its specific downstream UPR responses.

Responsibilities

In this placement, the student will be part of a cross-functional team within Research and Early Development, Respiratory and Immunology (R&I), building scientific knowledge around disease-causing molecular mechanisms and identification of novel targets for treatment. Specifically, the student will be working closely with a team investigating the role of ER stress in COPD and IPF.
 
Objectives and goals:
  1. Establish protocols to induce ER stress and monitor the UPR and associated respiratory disease-relevant biological pathways in primary lung cells.
  2.  Acquire extensive training in fundamental molecular and cell biology techniques, including qPCR, cell imaging, Western blot and other cellular/protein assays. 
  3. Contribute scientifically to the cross-functional ER stress team.
  4. Get insight in project work and drug discovery. 

Qualifications

Essential Requirements
  • Good networking skills and interpersonal skills.
  • Interest and curiosity in molecular biology and the experimental work behind drug discovery.
  • Ability to work independently.
  • Understanding of cell and molecular biology.
  • Written and oral communication skills in English.

Desirable Requirements 
  • Experience in cell culture.
  • Experience in molecular cell biology techniques eg. qPCR and Western blot.
  • Skilled in problem solving.

Application

Randstad Life Sciences is cooperating with AstraZeneca in this recruitment process. We only handle applications sent through Randstad’s website.

All chosen candidates need to pass a background check and an alcohol and drug test before starting the project.

Deadline for application: 2021-10-20

For more information: Veronika Knudsen [email protected] or Kerstin Karlsson [email protected]

About the company

At AstraZeneca, we turn ideas into life changing medicines and strive to continuously meet the unmet needs of patients worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.

Our Gothenburg site is one of AstraZeneca's three strategic science centers. We thrive in a multinational environment working cross-functionally across the globe with AstraZeneca colleagues as well as academic and industry partners. Our way of life is to foster a working environment that nurtures collaboration, openness and innovation. Therefore, we have created space for meetings, socializing and relaxation, where spontaneous meetings can give birth to new innovations. The unexpected ideas or thoughts that can come from a chat over something as simple as a cup of  coffee or a stroll on our “walk and talk” meeting trail. AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.

Arbetsgivare
Randstad AB
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CVRM research - metabolism in vitro team

Arbetsgivare / Ort: Randstad AB
Omfattning / Varaktighet: Heltid / 6 månader eller längre
Lönetyp: Fast månads- vecko- eller timlön
Ansök senast idag
Publicerad: 2021-10-11
Källa: Arbetsförmedlingen
VISA MER
Kvalifikationer
Arbetslivserfarenhet
Krav
  • Biolog

Om jobbet

Job description

Cardiovascular Renal and Metabolism (CVRM) Research – Metabolism In Vitro Team - Gothenburg

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because an opportunity no matter how small can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognising their potential.

The AstraZeneca CVRM Research group in Gothenburg is seeking to recruit a high calibre scientist to enable progression of a growing drug project portfolio. Highly motivated scientists are encouraged to apply for the opportunity to join our team of professionals who are passionate about advancing science, to discover and develop novel therapeutics that will benefit patients.
Role Overview

You will play an active role in implementing and executing scientific research and development within the CVRM Metabolism in vitro team, enabling the prosecution of a rapidly growing portfolio of small molecule and biologics drug projects. This is a "hands-on," laboratory based scientific and technical role in our in vitro metabolism team supporting projects from target validation to lead optimisation phases.
Role specifics

This position will be laboratory based and you will be responsible for several technical and experimental processes to support the CVRM Research group.

Responsibilities

  • Responsibility for design, execution and analysis of in vitro and ex vivo assays.
  • Predominantly functional and cellular screens supporting Target Validation, Lead Isolation and Lead Optimisation for the CVRM Research Area.
  • Communicate results, conclusions and recommendations to colleagues, line manager and multi-disciplinary teams.
  • Perform extended and specialized characterization when required for projects.
  • Record experiments in lab books and databases.
  • Play a leading role in assay development and optimization of disease relevant primary and transfected cell assays.
  • You would report to an expert member of staff and would be encouraged to be able to plan your daily work within direction set by your supervisor.
You will:
  • Be asked to provide interpretation of assay results
  • Work within a line and/or matrix/project team.
  • Demonstrates scientific rigor in assessing own data and that of others.

Qualifications

Essential
  • Be a "hands-on" expert with in vitro models and methodologies.
  • Enthusiasm for laboratory work, scientific curiosity
  • Experience in running in vitro biochemical and cellular assays to provide potency and activity readouts, including use of primary and recombinant cell lines.
  • Significant cell culture experience.
  • Experience of working with medium to high density microtitre plate technologies
  • Experience in data analysis and interpretation
  • Experience of working in accordance with established SOPs and codes of conduct.
  • Capability to work seamlessly with cross-functional project teams to provide high quality data in a timely manner.
  • Demonstrable ability to work within a line and/or matrix/ cross-functional project team.
  • Strong interest in providing materials and data for scientifically challenging work
  • Strong organizational, time management and communication skills
  • Strong, demonstrable analytical ability
  • Good oral and written communications skills
Desirable
  • Background in metabolic disease research areas.
  • Experience of working with disease relevant primary cell assays associated with one or more of the following disease areas: diabetes, obesity, NASH or dyslipidaemia.
  • Experience of use of robotics for assays and /or sample handling.
  • Experience working in pharmaceutical or biotech environment
Behavioral competencies
  • Hard working, organized, balanced and meticulous with an ability to work well under pressure.
  • Adaptable and a team player with a conscientious attitude and enthusiasm.
  •  Desire to learn and build on the role

Education
Degree in one of the Life Sciences disciplines and equivalent post-graduate or industry experience.

Application

Deadline 2021-10-17, selection and interviews will be ongoing. The position may be filled before the last day of application, therefore, apply as soon as possible.

For more information: Kerstin Karlsson [email protected] or Veronika Knudsen [email protected]

About the company

Randstad Life Sciences specializes in the field of science and is part of Randstad, the world leader in recruitment and consulting with operations in 38 countries. With this global network, in combination with our strong local foundation, we can offer a wide range of varied and developing assignments and jobs for you who are a specialist in life science. Our mission is to help you reach your true potential with your career in focus!

Arbetsgivare
Randstad AB
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Thesis work: 30 credits, AstraZeneca Gothenburg

Arbetsgivare / Ort: Randstad AB
Omfattning / Varaktighet: Heltid / 6 månader eller längre
Lönetyp: Fast månads- vecko- eller timlön
Ansök senast idag
Publicerad: 2021-10-01
Källa: Arbetsförmedlingen
VISA MER
Kvalifikationer
Arbetslivserfarenhet
Krav
  • Biolog

Om jobbet

Job description

Developing a method for characterizing and improving  stem cell differentiation

Are you a master student with a hunger for science and eager to learn more about stem cell differentiation and the next generation therapeutics? Do you like molecular and cellular biology techniques and are looking for an inspiring master thesis project starting in the spring 2022? Then this project at the new Cell Therapy Department at AstraZeneca could be interesting to You!

Thesis project: 30 credits
Student location: AstraZeneca, Gothenburg, Sweden
Start: January 2022

Introduction
Biopharmaceuticals R&D is now building a new cell therapy department with the goal to establish AstraZeneca as a world-leader in the stem cell field and to build a competitive pipeline within cell therapy across disease areas within Cardiovascular, Renal and Metabolism (CVRM) and Respiratory and Inflammation (R&I). By directing differentiation of pluripotent stem cells into precursor cells or to mature cell types, novel therapies can be developed targeting a wide range of diseases such as heart failure, kidney and liver diseases.

The project aims to develop a novel analytical method that will be used for optimizing differentiation protocols.

Responsibilities

The primary focus of the project will be to culture pluripotent stem cells and differentiate them towards cardiac cells. Samples from the differentiation process will be collected and analyzed, e.g. using ELISA and flow cytometry. 

Qualifications

  • A strong interest in stem cell science.
  • Highly motivated, having a scientific mindset and can easily comprehend and apply ideas from the literature. 
  • Ability to watch & learn, and then perform experiments on your own, with some guidance.
  • Good organizational skills.
  • Written and oral communication skills in English.
  • Cell culture experience. 

Application

Randstad Life Sciences is cooperating with AstraZeneca in this recruitment process. We only handle applications sent through Randstad’s website.

All chosen candidates need to pass a background check and an alcohol and drug test before starting the project.

Deadline for application: 2021-10-20

For more information: Veronika Knudsen [email protected] or Kerstin Karlsson [email protected]

About the company

At AstraZeneca, we turn ideas into life changing medicines and strive to continuously meet the unmet needs of patients worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.

Our Gothenburg site is one of AstraZeneca's three strategic science centers. We thrive in a multinational environment working cross-functionally across the globe with AstraZeneca colleagues as well as academic and industry partners. Our way of life is to foster a working environment that nurtures collaboration, openness and innovation. Therefore, we have created space for meetings, socializing and relaxation, where spontaneous meetings can give birth to new innovations. The unexpected ideas or thoughts that can come from a chat over something as simple as a cup of  coffee or a stroll on our “walk and talk” meeting trail. AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.

Arbetsgivare
Randstad AB
Ansökan
Ansök senast idag

Ansök här
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Thesis work: Clearing for Lung Tissue Transparency-3D imaging

Arbetsgivare / Ort: Randstad AB
Omfattning / Varaktighet: Heltid / 6 månader eller längre
Lönetyp: Fast månads- vecko- eller timlön
Ansök senast 22 oktober (2 dagar kvar)
Publicerad: 2021-10-08
Källa: Arbetsförmedlingen
VISA MER
Kvalifikationer
Arbetslivserfarenhet
Krav
  • Biolog

Om jobbet

Job description

Clearing for Lung Tissue Transparency – towards 3D imaging

Thesis project:
30 credits
Student location:
AstraZeneca, Gothenburg, Sweden
Start:
January 2022

Did you know organs can be made transparent and be imaged in 3D? If you are interested in working with 3D imaging of lung in a group with advanced imaging labeling techniques – please come join the Swedish Imaging Hub at Imaging and data analytics, CPSS (clinical and pharmacological safety sciences) for you master thesis.

Now that we have developed clearing protocols for creating transparent organs a number of questions about exactly what can be viewed, how structures are connected to eachother, in what magnification can the tissues be viewed and how many things can we label and investigate at the same time. The organ we will start exploring this in is the lung. Lung tissues have a complex matrix of heterogenic molecules, for example elastin, collagen and phospholipids in cell membranes. Our clearing method remove many of these heterogenous molecule while proteins and carbohydrates that are covalently bound to the matrix and each other are still preserved, making us able to label what is of interest with fluorescent tags and image them. At first we will focus in imaging a lot of the important proteins naturally occurring in the lung together with inhaled drugs and on top of that explore capturing a detailed 3D view of disease related phenotypes like inflammation and tumors. You will join an organization at AZ focusing on Imaging, imaging analyses and how to use artificial intelligence to support the image analyses. The organization is a part of AZ that works with safety concerns which might arise during drug development.

Responsibilities

By joining our team you will learn techniques and principles around tissue labelling and imaging. You will learn to appreciate how important imaging is during scientific trouble shouting and drug development. The goal of your particular project will be to:

  • Further improve the clearing protocol in particular to speed up the clearing and labeling process.
  • Test different labeling techniques to get the most out of the 3D information as possible
  • Evaluate the 3D high resolution images and support the development of digital image analyses to quantitatively determine numbers and volume measurements

Qualifications

Essential Requirements
  • You have at least 2 years of studies at the University
  • English communication skills
  • Commit to labwork
  • Thorough
  • Responsive
Desirable Requirements 
  • Science focused
  • Creative

Application

Randstad Life Sciences is cooperating with AstraZeneca in this recruitment process. We only handle applications sent through Randstad’s website.

All chosen candidates need to pass a background check and an alcohol and drug test before starting the project.

Deadline for application: 2021-10-22

For more information: Veronika Knudsen [email protected] or Kerstin Karlsson [email protected]

About the company

At AstraZeneca, we turn ideas into life changing medicines and strive to continuously meet the unmet needs of patients worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.

Our Gothenburg site is one of AstraZeneca's three strategic science centers. We thrive in a multinational environment working cross-functionally across the globe with AstraZeneca colleagues as well as academic and industry partners. Our way of life is to foster a working environment that nurtures collaboration, openness and innovation. Therefore, we have created space for meetings, socializing and relaxation, where spontaneous meetings can give birth to new innovations. The unexpected ideas or thoughts that can come from a chat over something as simple as a cup of  coffee or a stroll on our “walk and talk” meeting trail. AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.

Arbetsgivare
Randstad AB
Ansökan
Ansök senast 22 oktober (2 dagar kvar)

Ansök här
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